Understanding the Impact of CYP2C9*2*3 Alleles on Sulphonylureas in Type 2 Diabetes

  • 7 months ago
Sulphonylureas are a class of oral antidiabetic drugs commonly used in the treatment of type 2 diabetes. They work by stimulating the release of insulin from the beta cells of the pancreas, which helps to lower blood sugar levels and improve glucose metabolism.

The mechanism of action of sulphonylureas involves binding to specific receptors on the beta cells, leading to an increase in insulin secretion. This increase in insulin helps to facilitate the uptake of glucose by cells, reducing the amount of glucose in the bloodstream.

Sulphonylureas are known for their effectiveness in lowering blood sugar levels and achieving glycemic control in patients with type 2 diabetes. However, like any medication, they may have side effects and considerations that need to be taken into account.