Cancer Study Detects Patterns in DNA, Could Lead to Personalized Treatments
- 2 years ago
Cancer Study , Detects Patterns in DNA, , Could Lead to
Personalized Treatments.
The study was conducted by researchers at the University of Cambridge.
After an analysis of more than 12,000 cancerous tumors, researchers have been able to pinpoint clues left behind by the DNA of the disease.
Such knowledge can assist physicians in specific treatments geared toward a patient's particular cancer diagnosis. .
It’s like looking at a very busy beach with thousands of footprints in the sand. , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
To the untrained eye, the footprints appear to be random and meaningless, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
But if you are able to study them closely, you can learn a lot about what’s been going on, distinguish between animal and
human prints, , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
... whether it’s an adult or child, what direction they’re traveling in, etc. It’s the same thing with the mutational signatures. , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
The use of whole genome sequencing can identify which ‘footprints’ are relevant/ important and reveal what’s happened through the development of the cancer, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
Researchers recognized 58 mutational signatures of cancer that had not yet been articulated.
This means that cancer likely has causes that are currently unknown. .
Study authors say that such knowledge can lead to a discovery of the "Achilles heel" of specific cancers.
The reason it is important to identify mutational signatures is because they are like fingerprints at a crime scene – they help to pinpoint cancer culprits, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
Some mutational signatures have clinical or treatment implications – they can highlight abnormalities that may be targeted with
specific drugs... , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
... or may indicate a
potential ‘Achilles heel’
in individual cancers, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'
Personalized Treatments.
The study was conducted by researchers at the University of Cambridge.
After an analysis of more than 12,000 cancerous tumors, researchers have been able to pinpoint clues left behind by the DNA of the disease.
Such knowledge can assist physicians in specific treatments geared toward a patient's particular cancer diagnosis. .
It’s like looking at a very busy beach with thousands of footprints in the sand. , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
To the untrained eye, the footprints appear to be random and meaningless, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
But if you are able to study them closely, you can learn a lot about what’s been going on, distinguish between animal and
human prints, , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
... whether it’s an adult or child, what direction they’re traveling in, etc. It’s the same thing with the mutational signatures. , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
The use of whole genome sequencing can identify which ‘footprints’ are relevant/ important and reveal what’s happened through the development of the cancer, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
Researchers recognized 58 mutational signatures of cancer that had not yet been articulated.
This means that cancer likely has causes that are currently unknown. .
Study authors say that such knowledge can lead to a discovery of the "Achilles heel" of specific cancers.
The reason it is important to identify mutational signatures is because they are like fingerprints at a crime scene – they help to pinpoint cancer culprits, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
Some mutational signatures have clinical or treatment implications – they can highlight abnormalities that may be targeted with
specific drugs... , Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'.
... or may indicate a
potential ‘Achilles heel’
in individual cancers, Dr. Serena Nik-Zainal, Lead Study Author,
via 'The Guardian'