With the tagline, “Undetectable Means Untransmissible”, the development of PREP is the next step in the management of the epidemic. Are we following the science? Melisa Idris and Sharaad Kuttan speak to Professor Datuk Dr Adeeba Kamarulzaman, President, International AIDS Society, Vice-President (Malaysian AIDS Council) and the dean of the Faculty of Medicine at Universiti Malaya.