They say opposites attract. Milly (Toni Collette) is the woman who has everything: a successful career; a devoted husband and two gorgeous kids. Her best friend is Jess (Drew Barrymore), whoworks in a community garden, lives in a boathouse with her boyfriend Jago and desperately wants a baby.

Friends since childhood, Jess and Milly can't remember a time they didn't share everything - secrets, clothes, even boyfriends, their differences are the glue that binds them together. That is until Milly is hit with the life changing news that she has breast cancer and needs Jess' support more than ever.