In Order For Weight Loss To Be Permanent, Changes In Diet And Lifestyle Must Be Permanent As Well. There Is Evidence That Counseling Or Exercise Alone Do Not Result In Weight Loss, Whereas Dieting Alone Results In Meaningful Long-Term Weight Loss, And A Combination Of Dieting And Exercise Provides The Best Results. Meals Replacement, Orlistat And Very-Low-Calorie Diet Interventions Also Produce Meaningful Weight Loss.