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Alex gives Kara a pep talk before going out to face a powerful new threat - Reign.

Supergirl traces the origins of a mysterious symbol to an ancient prophecy and the mark of the World Killer, Reign.

Director: Glen Winter
Writers: Jerry Siegel (based on characters created by), Joe Shuster (based on characters created by)
Stars: Melissa Benoist, Mehcad Brooks, Chyler Leigh