Could Meredith Grey's original "person" be returning to ABC's "Grey's Anatomy?" Many fans were distraught when Meredith's best friend, Cristina (played by Sandra Oh) left the show. Her dry humor and drive for success were an integral part of the drama. If Cristina's on-screen ex, Owen (played by Kevin McKidd) had his way, she would definitely return. In an interview with Entertainment Tonight, McKidd admitted they were his favorite couple on the show and they still speak all the time.