The fourth cycle of Asia's Next Top Model aired from March to June 2016. The judging panel was completely replaced; Thai model Cindy Bishop was appointed as host and head judge, and Indonesian model Kelly Tandiono as model mentor and judge. Yu Tsai joined the show as creative consultant.

The cycle featured 14 contestants, three from the Philippines, two from Indonesia and Thailand, and one each from Hong Kong, Malaysia, Mongolia, Myanmar, Singapore, South Korea and Vietnam. China, India, Japan, Nepal and Taiwan were unrepresented.

Among the prizes were a Subaru XV, a position as the face of TRESemmé, a cover and fashion spread in Harper's Bazaar Singapore and a modeling contract with Storm Model Management in London.

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