Donald Trump scored victories Tuesday in three states, including the big-prize Florida, but lost Ohio to the state's governor, John Kasich, as the billionaire continued to move ahead in his stunning campaign for the Republican presidential nomination.
Hillary Clinton won at least four states, dealing a severe blow to Bernie Sanders' bid to slow her march toward the Democratic nomination.
Marco Rubio, the Florida senator who staked his once-promising campaign on winning in his home state, dropped out of the presidential race shortly after the polls closed.
That leaves Kasich as the last true establishment candidate running against Trump and arch-conservative Texas Sen. Ted Cruz.
Tuesday's votes in five states had been viewed as a pivotal moment in the Republican presidential campaign.
For the first time, two states - Ohio and Florida - had winner-take-all contests.
A Trump sweep could have given him an insurmountable lead in the delegate count.