This new therapy could teach the human body how to destroy cancer cells
- 8 years ago
SEATTLE — Scientists in the U.S. and in Italy are developing a revolutionary cancer therapy that would teach the body to destroy cancer cells on its own, reducing the need for debilitating chemotherapy treatments.
The new technique developed by the Cancer Research Center in Seattle, involves removing T-cells from patients, and genetically modify them by adding chimeric antigen receptors, or CARs, from genetically engineered mice. The modified T-cells are then injected back into the patient's body, and are able to target and destroy cancer cells.
The therapy is similar to a treatment given last year to British baby Layla Richards, who was diagnosed with Acute Lymphoblastic Leukemia, a disease in which the bone marrow makes too many immature lymphocytes, Sky News reported.
Richards received her treatment at Great Ormond Street Hospital in central London and was left cancer-free.
Recent T-cell immunotherapy trials have shown great results also in the U.S. More than 40 patients with different types of blood cancers were treated, and more than half of them were left cancer-free.
Among patients with terminal leukemia, 94 percent went into remission. Being in remission, however, still implies the cancer could eventually return.
In a second major breakthrough in Italy, researchers at the University of Milan have discovered that memory T-cells can stay in the body for at least 14 years, according to a study published on the San Raffaele Hospital website.
This means the cells could be trained to fight cancer as well as to remember the disease in case it comes back, allowing them to defeat it again. The latest discovery gives hope for the development of a vaccine-style drug that could stop cancer from coming back once it has been defeated.
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The new technique developed by the Cancer Research Center in Seattle, involves removing T-cells from patients, and genetically modify them by adding chimeric antigen receptors, or CARs, from genetically engineered mice. The modified T-cells are then injected back into the patient's body, and are able to target and destroy cancer cells.
The therapy is similar to a treatment given last year to British baby Layla Richards, who was diagnosed with Acute Lymphoblastic Leukemia, a disease in which the bone marrow makes too many immature lymphocytes, Sky News reported.
Richards received her treatment at Great Ormond Street Hospital in central London and was left cancer-free.
Recent T-cell immunotherapy trials have shown great results also in the U.S. More than 40 patients with different types of blood cancers were treated, and more than half of them were left cancer-free.
Among patients with terminal leukemia, 94 percent went into remission. Being in remission, however, still implies the cancer could eventually return.
In a second major breakthrough in Italy, researchers at the University of Milan have discovered that memory T-cells can stay in the body for at least 14 years, according to a study published on the San Raffaele Hospital website.
This means the cells could be trained to fight cancer as well as to remember the disease in case it comes back, allowing them to defeat it again. The latest discovery gives hope for the development of a vaccine-style drug that could stop cancer from coming back once it has been defeated.
-------------------------------------------------------------
Welcome to TomoNews, where we animate the most entertaining news on the internets. Come here for an animated look at viral headlines, US news, celebrity gossip, salacious scandals, dumb criminals and much more! Subscribe now for daily news animations that will knock your socks off.
Visit our official website for all the latest, uncensored videos: http://us.tomonews.net
Check out our Android app: http://bit.ly/1rddhCj
Check out our iOS app: http://bit.ly/1gO3z1f
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Instagram @tomonewsus http://instagram.com/tomonewsus