Melissa McCarthy - Samantha Who? 1x01

Jennifer Esposito, Melissa McCarthy, and Ben Falcone Made Silly Movies on Weekends During ‘Samantha Who?’

Melissa McCarthy - Samantha Who? 1x03

Melissa McCarthy - Samantha Who? 1x02

Melissa McCarthy Crashed Christina Aguilera’s Carpool Karaoke

Christina Applegate Clapped Back at a Newscaster Who Called a Wheelchair Model Ridiculous

Melissa McCarthy Has Harsh Words for Women Who Aren't Feminists

We Share Extremely Sad News About 51-year-Old Actress Christina Applegate, Goodbye Applegate

Streets 1990 Thriller Christina Appelgate Christina Applegate singing at Backstage BAR. part 3/4

Streets 1990 Thriller Christina Appelgate Christina Applegate singing at Backstage BAR. part 1/4

Streets 1990 Thriller Christina Appelgate Christina Applegate singing at Backstage BAR. part 4/4

Streets 1990 Thriller Christina Appelgate Christina Applegate singing at Backstage BAR. part 2/4

Embrujada -1x01- I, Darrin, Take This Witch, Samantha (Yo, Darrin, quiero a esta bruja, Samantha...)

Christina Applegate Has Multiple Sclerosis

Christina Applegate Reveals MS Diagnosis _ E News

Christina Applegate Reveals Multiple Sclerosis Diagnosis

Christina Applegate Reveals Multiple Sclerosis Diagnosis

Christian Slater & Christina Applegate Kill Any Dating Rumors-4QHVUAAp7lY

Christina Applegate says she 'probably won't act again'

Christina Applegate Says She's Likely Done With On-Camera Work

Christina Applegate Calls Out Candace Owens Over Insensitive Remarks Over