There are currently four games based on the Strike Witches franchise. While mainly based on the characters featured in the anime, characters from the two manga series also appear in some of the games. The first three Strike Witches games will have the same opening "private wing" by Yoko Ishida

Strike Witches: Blitz in the Blue Sky - New Commander Struggles! (ストライクウィッチーズ -蒼空の電撃戦 新隊長 奮闘する！- Sutoraiku Witchīzu: Sōkū no Dengekisen - Shin Taicho Funtousuru!?), is a simulation game developed by Russell Games[25] for the Nintendo DS and released on November 26, 2009. It features Junko Takei. The Witches take under their wing a candidate commanding officer from the Fuso Empire, Junko. She contacts the 501st to inform them that she will be meeting up with them during a training exercise. At the same time the military announces a new operation: to make a concerted strike against the Neuroi at the Gallian coastline and establish a new frontline base. Pre-orders for the Nintendo DS version received a fake girl's gym shorts DS pouch with their order.[26]

Strike Witches: What I Can Do Along With You - A Little Peaceful Days (ストライクウィッチーズ -あなたとできること A Little Peaceful Days- Sutoraiku Witchīzu: Anata to Dekiru Koto - A Little Peaceful Days?) is a visual novel title also developed by Russell Games for PlayStation 2, which was released on May 27, 2010. This adventure game features Amaki Suwa and Nishiki Nakajima.[27] To the south of the base lies a deserted island where the Witches are conducting open-air exercises. However, when the carrier they are stationed on comes under surprise Neuroi attack, the Witches are left stranded. In the two weeks that it will take for reinforcements to arrive, the Witches decide to carry on with their maneuvers, as well as make sure they can survive.

Strike Witches: Silver Wing (ストライクウィッチーズ 白銀の翼 Sutoraiku Witchīzu: Hakugin no Tsubasa?), is a bullet hell shoot 'em up developed by Cyberfront[28] for Xbox 360. Players control a group of three witches, and change positions to best defend against the Neuroi. And this game also features Junko Takei, with Nishiki Nakajima as a downloadable character.[29] It was released in Japan on July 29, 2010. In Jun 28, 2012, this game also available in PSP. Everything in Xbox 360 version also available in PSP version.

A fourth game, Strike Witches 2: Heal, Cure and Squish (ストライクウィッチーズ2 いやす・なおす・ぷにぷにする Sutoraiku Witchīzu: Iyasu Naosu Punipuni suru?), was developed by Kadokawa Shoten for Nintendo DS. The game features tactical shootouts between Witches, as well as minigames in which the players massages one of the Witches. It was released in Japan on October 21, 2010.